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Alzheimer’s Doesn’t Begin With Alzheimer’s: The Early Warning Signs Most People Miss

Written by Jason Rowell | Jun 16, 2026 1:34:27 PM

By Dr. Gregory C. Fors
Board Certified Chiropractic Neurologist
Chief Science Officer, BioSpec Nutritionals

June is Alzheimer’s Awareness Month, making it an appropriate time to discuss one of the most feared health conditions affecting aging adults.

This topic is deeply personal for me.

My mother suffered from Alzheimer’s disease. Like millions of families, I watched first hand as memory, independence, personality, and quality of life gradually slipped away from someone I loved deeply.

This experience helped fuel a lifelong interest in understanding how the brain works, why cognitive decline occurs, and most importantly, what can be done to reduce risk and preserve cognitive function.

As a Board Certified Chiropractic Neurologist, I have spent decades studying the nervous system, educating doctors, and helping patients with brain fog, memory problems, chronic pain, sleep disorders, metabolic dysfunction, and neurodegenerative conditions.

Over the years I have attended numerous educational seminars taught by Dr. Dale Bredesen, one of the pioneers in functional medicine approaches to cognitive decline. Most recently, I attended the Personalized Lifestyle Medicine Institute Brain Conference in Chicago in May 2026, where Dr. Bredesen once again shared emerging research regarding Alzheimer’s disease and cognitive decline.

One of the most important lessons I have learned from Dr. Bredesen’s work and from caring for patients over several decades is this:

Alzheimer’s Disease Rarely Begins As Alzheimer’s Disease

Most people assume Alzheimer’s disease suddenly appears late in life. In reality, the biological processes that contribute to Alzheimer’s disease often begin twenty to thirty years before a diagnosis is ever made.

The earliest warning signs are frequently subtle. You may notice:

  • Difficulty finding words
  • Forgetting names
  • Losing your train of thought
  • Reduced concentration
  • Increased mental fatigue
  • Brain fog
  • Difficulty multitasking
  • Poor sleep
  • Increased stress sensitivity
  • Feeling mentally slower than you once did

Because these changes seem minor, many people dismiss them as normal aging. I do not.

In many individuals, these symptoms represent early warning signs that the brain is under stress and beginning to lose resilience. The encouraging news is that many of the biological factors driving cognitive decline are modifiable. The earlier they are identified, the greater our opportunity to change the trajectory.

Why This Matters To Me Personally

A couple of decades ago, I discovered that I was developing insulin resistance myself.

Like many people, I felt healthy. I exercised, maintained a healthy weight, and generally took good care of myself. Yet laboratory testing revealed that my metabolism was beginning to move in the wrong direction.

This discovery became a turning point. I became much more intentional about controlling blood sugar, reducing insulin spikes, increasing physical activity, improving sleep, and utilizing targeted nutritional support.

Today, as I celebrate my 75th year, I continue to enjoy excellent cognitive function, strong energy levels, an active professional life, and a passion for helping others improve their health. My experience reinforced something I have observed repeatedly in clinical practice: Many of the processes that eventually contribute to Alzheimer’s disease begin decades before symptoms appear.

Quick Self-Assessment

Ask yourself:

  • Do you frequently forget words during conversation?
  • Do you lose your train of thought?
  • Are names harder to remember?
  • Are you having greater difficulty concentrating?
  • Do you feel mentally slower than several years ago?
  • Are you struggling more with multitasking?
  • Are family members noticing memory changes?
  • Are you experiencing increasing brain fog?
  • Are you sleeping poorly?
  • Do routine tasks feel more mentally exhausting?

Checking several of these boxes does not mean you have Alzheimer’s disease. It does mean your brain deserves attention.

Alzheimer’s Is Not One Disease

One of the most important concepts emerging from modern neuroscience is that Alzheimer’s disease is not a single disease process. Instead, it is often the result of multiple biological stressors occurring simultaneously. Dr. Bredesen has described several common patterns that contribute to cognitive decline:

  • Inflammatory Alzheimer’s: Driven by chronic inflammation from poor diet, insulin resistance, obesity, gut dysfunction, chronic infections, and environmental toxins.
  • Glycotoxic Alzheimer’s: Driven by insulin resistance, elevated insulin levels, elevated blood sugar, and metabolic syndrome. This is one of the most common patterns I encounter clinically.
  • Atrophic Alzheimer’s: Associated with deficiencies in hormones, nutrients, growth factors, and trophic support required by healthy neurons.
  • Toxic Alzheimer’s: Associated with mold toxins, heavy metals, environmental chemicals, and chronic infections.
  • Vascular Alzheimer’s: Associated with reduced blood flow and impaired circulation to the brain.
  • Traumatic Alzheimer’s: Associated with prior concussions and head injuries.

Why Alzheimer’s Is Increasingly Called “Type 3 Diabetes”

If there is one factor I routinely find beneath chronic disease, it is insulin resistance. Insulin resistance contributes to heart disease, stroke, obesity, Type 2 diabetes, fatty liver disease, certain cancers, and Alzheimer’s disease.

When insulin remains elevated year after year, the brain gradually loses its ability to efficiently utilize glucose for fuel. The result is:

  • Reduced cellular energy production
  • Increased oxidative stress
  • Increased inflammation
  • Impaired memory
  • Accelerated aging of brain tissue

Many patients tell me, “My memory just isn’t what it used to be.” In many cases, the problem is not aging. The problem is metabolic dysfunction.

I am far less interested in waiting for Alzheimer’s disease to develop than I am in identifying the metabolic, inflammatory, nutritional, vascular, and lifestyle factors that create the conditions for Alzheimer’s disease decades earlier. Those are the factors we can actually do something about.

Brain Fog Is Not Always Benign

One of the greatest misconceptions regarding Alzheimer’s disease is that it begins with severe memory loss. It usually does not. In many cases the progression looks something like this:

Insulin Resistance → Brain Fog → Cognitive Fatigue → Mild Cognitive Impairment → Dementia

This process may unfold over decades. That means there is tremendous opportunity for intervention. The goal is not simply treating Alzheimer’s disease. The goal is preventing the biological environment that allows Alzheimer’s disease to develop.

Final Thoughts

For decades, Alzheimer’s disease was viewed as an inevitable consequence of aging. The emerging science tells a different story. While genetics matter, lifestyle factors appear to play an enormous role in determining whether the brain remains resilient or gradually declines.

My goal is not simply to help individuals live longer. My goal is to help other doctors help their patients maintain clear thinking, independence, meaningful relationships, and the ability to enjoy life for as many years as possible. That journey begins long before a diagnosis of Alzheimer’s disease.

It begins today. Take control of your health. There is hope.

Coming Next

In Part 2 of this Alzheimer’s Awareness Series, I will discuss the lifestyle, nutrition, exercise, sleep, and nutritional supplement strategies that may help support healthy cognitive aging and reduce the risk of cognitive decline. We will dive deep into:

Biospec Nutritionals — Medical & Educational Disclaimer
This content is provided for educational and informational purposes only and is not intended to provide medical advice, diagnosis, or treatment. It is not a substitute for individualized guidance from a qualified healthcare professional. Always consult your physician or other qualified healthcare provider before starting, stopping, or changing any supplement, medication, diet, or exercise program.
† FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Selected References

    1. Bredesen DE. J Alzheimers Dis. 2022;88(4):1411-1421.
    2. Bredesen DE et al. J Alzheimers Dis. 2018;64(3):885-898.
    3. Livingston G et al. Lancet. 2024.
    4. De la Monte SM. J Diabetes Sci Technol. 2008.
    5. Craft S. Arch Neurol. 2012.
    6. Ngandu T et al. Lancet. 2015.
    7. Arnold SE et al. Nat Rev Neurol.
    8. Jack CR Jr et al. Alzheimers.